The relationship between aspartate aminotransferase (AST) and alanine aminotransferase (ALT) levels, when expressed as a quotient, can provide valuable diagnostic information. The AST to ALT ratio involves dividing the AST level by the ALT level. For instance, an AST level of 100 U/L and an ALT level of 50 U/L would yield a ratio of 2.0.
This quotient serves as an indicator of the type and severity of liver damage. Historically, it has been used to differentiate between various liver conditions, such as alcoholic liver disease and non-alcoholic fatty liver disease. Specific ratio thresholds can suggest particular underlying etiologies, aiding in the diagnostic process and influencing subsequent clinical management decisions. The derived value, in conjunction with other clinical and laboratory findings, provides a more nuanced understanding of hepatic health.