This tool estimates kidney function by determining the volume of fluid filtered from the blood by the kidneys per unit of time. This calculation typically incorporates serum creatinine levels, age, sex, and race to provide a more accurate assessment of renal clearance. For example, a person with elevated serum creatinine may have a reduced value, indicating impaired kidney function.
Accurate determination of kidney function is critical for diagnosing and managing kidney disease, adjusting medication dosages, and monitoring the progression of renal impairment. Historically, direct measurement of this value was complex and invasive, making estimation equations a valuable clinical alternative. The adoption of these estimating equations has improved the identification of chronic kidney disease and facilitated timely interventions to slow its progression.
