The assessment of relative concentrations of two protein types in blood serum, albumin and globulins, yields a value that serves as an indicator of overall health status. This value is derived through a calculation process, dividing the albumin concentration by the globulin concentration. For example, if a patient’s albumin level is 4.0 g/dL and globulin level is 2.0 g/dL, the resulting value would be 2.0. This resulting value requires careful interpretation within the context of a broader clinical evaluation.
This calculation plays a role in initial diagnostic screening. Deviations from established reference ranges may indicate a variety of conditions, spanning from liver disease and kidney dysfunction to certain autoimmune disorders and infections. Historically, manual laboratory methods were employed to determine the protein concentrations. Modern clinical practice incorporates automated analyzers, but the fundamental mathematical relationship remains constant. This assessment aids healthcare professionals in risk stratification and informs subsequent diagnostic procedures.
